FEBUTAZ 80MG (FEBUXOSTAT)
FEBUTAZ 80MG is a prescription medication used to treat gout and hyperuricemia (elevated levels of uric acid in the blood). It works by decreasing the production of uric acid in the body, which can help prevent gout attacks and reduce the risk of kidney stones. Each tablet contains 80mg of febuxostat, the active ingredient that helps to lower uric acid levels. This medication is typically taken once daily with or without food, as directed by your doctor.
HOW FEBUTAZ 80MG WORK?
This drug belongs to the class of xanthine oxidase inhibitors. It works by inhibiting the enzyme xanthine oxidase, then inhibits the conversion of hypoxanthine to xanthine to uric acid without affecting the enzymes involved in the synthesis of purines and pyrimidines.
HOW TO TAKE FEBUTAZ 80MG?
- Swallow the tablets with a glass of water. Do not chew, crush, or break
- You should take this medicine for as long as you are prescribed.
- You can take the tablet with or without food. as per your doctor’s prescription.
DOSAGE
Missed dose
If you miss a dose of FEBUTAZ 80mg, take it as soon as you remember. If it is almost time for the next dose, skip it and take the next one. Do not double the dose to make up for it.
Overdose
Seek emergency medical attention or contact your doctor in case of overdose.
INTERACTIONS
All drugs interact differently from person to person.
Interaction with medicine
- Azathioprine
- Theophylline
Interactions with the disease
Secondary hyperuricemia
This medicine is not recommended in patients with malignant disease, tumor lysis syndrome, or Lesch-Nyhan syndrome in whom uric acid levels are very high.
Interaction with alcohol
The interaction with alcohol is unknown. It is advisable to consult a doctor before use.
SIDE EFFECTS
Major and minor side effects for FEBUTAZ 80mg tablets are;
- Abdominal pain
- Unexpected weight gain or loss
- Throat irritation
- Blurred vision
- Itching or rash
- Pale skin
- Yellow-colored eyes or skin
- Chest discomfort
- Fast heartbeat
- Decreased interest in sexual intercourse
WARNINGS AND PRECAUTIONS
Warnings for Women
Pregnancy: pregnant women cannot use this medicine
Breastfeeding: Breastfeeding women cannot take this medicine
GENERAL WARNINGS
Exacerbation of gout
Flare-ups of gout may occur after starting treatment due to changes in serum uric acid levels. Stop treatment until symptoms disappear completely. At the same time, prevention of exacerbation of gout with nonsteroidal anti-inflammatory drugs or colchicines should be started for up to 6 months.
Cardiovascular events
This medication is not recommended in patients with coronary artery disease due to the risk of cardiovascular thromboembolic events such as myocardial infarction, stroke.
Liver dysfunction
This medication is known to cause liver failure. Obtain baseline liver function tests before starting treatment. Treatment should be discontinued if the level of alanine aminotransferase (ALT) exceeds the reference range by more than 3 times.
Impaired renal function
The drug should be used with caution in patients with severe renal impairment (CrCl less than 30 ml/min).
Asymptomatic hyperuricemia
This medication is not recommended for patients with asymptomatic hyperuricemia.
STORAGE
Store in a cool, dry place out of the reach of children. Do not use the medicine after the expiry date.